Langya virus, the new zoonotic virus identified in China

Langya virus, the new zoonotic virus identified in China

Recently, a new zoonotic virus, Langya henipa virus, remains a matter of concern.

It may be noted that the first case of Langya virus was reported in the year 2019. Langya virus is classified among the biosafety level-4 (BSL4) pathogens.

Biosafety Levels

  • BSL is used to identify protective measures needed in a laboratory setting to protect workers, the environment, and the public.
  • Activities and projects conducted in biological laboratories are classified by biosafety level.
  • The four biosafety levels are BSL-1, BSL-2, BSL-3 and BSL-4, with BSL-4 being the highest (maximum) level of control.Langya virus, the new zoonotic virus identified in China

‘Langya’ virus

  • Langya virus is a zoonotic virus, which means it can be transmitted from animals to humans.
  • Langya is part of the genus Henipavirus, which has a single-stranded RNA genome with a negative orientation.
  • The unique features of the Henipavirus Paramyxovirinae are their large genomes, long uncharacterized regions that make it an emerging cause of zoonosis in the Asia-Pacific region.

Novel Langya henipavirus (LayV)

  • The newly discovered Langya virus is a phylogenetically distinct Henipavirus.
  • Other viruses of the previously discovered Henipavirus types are Mojiang, Ghanian, Cedar, Nipah and Hendra.
  • Of these, Nipah and Hendra are known to cause fatal diseases in humans.
  • The genome organization of langya is “similar to that of other henipaviruses”, and is closely related to the “Mojiang henipavirus” that was discovered in southern China.
  • Symptoms caused by this virus include fever, fatigue, cough, nausea, headache, loss of appetite, etc.
  • There are no licensed drugs or vaccines for humans to treat it. Langya virus can be potentially fatal to humans in case of severe infection.
  • Langya belongs to the same family of viruses as the deadly Nipah virus that is commonly found in bats.

Source – The Hindu

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